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RDs find themselves counseling patients who are curious or take these medications and often are peppered with questions about their actions, side effects, and implications for short- and long-term use

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To address this, an alternate design could have been to test consecutive day dosing and then have a washout period and then test the alternate day dosing

Understanding the timeline helps with planning and expectations

Neurological symptoms deserve particular attention

There is also growing interest in whether these medications have tissue-level anti-inflammatory effects beyond weight loss alone