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9 One randomized placebo-controlled trial that included 96 subjects greater than 70 years old and suffering from fatigue, most of whom also reported poor concentration or impaired memory, found treatment with 2 grams acetyl-L-carnitine twice daily for 180 days not only improved scores on a screening test of overall cognitive status (the MMSE), but also reduced mental and physical fatigue, fatigue after exercise, sleep problems, and muscle pain

diacetylbis(4-methylthiosemicarbazonato) copper] is a redox-active molecule involved in redox cycling between oxidized CuII and reduced CuI, that is showing promise as a potential therapeutic in ALS (Hilton et al., 2020)

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For competitive athletes, IGF-1 and its analogs, including LR3, are banned at all times, in and out of competition, under Section S2 of WADA's Prohibited List (Peptide Hormones, Growth Factors, Related Substances and Mimetics)

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Kaur 2014